Welcome to the RUFUS trial website where you can learn more about the study. RUFUS is an MRC-funded study aimed at studying the repurposing of flumazenil for intramuscular treatment of coma due to unintentional drug overdose.

Learn more about the background to the study

Read about the aims and outcomes of the study

Details of study design and trial stages

Details on study team and Trial Management Group 

Trial Steering Committee and Data Monitoring Committee members

Read about the latest news and updates on the study as it progresses

Details on Patient and Public Involvement for the trial

Read about how the trial progresses and updates on recruitment