Information on the research interests, projects, and members of Gillian Gray's Research Group. Image Dr Gillian Gray Reader Research Survival following acute myocardial infarction (MI), or heart attack, has increased thanks to efficient intervention to restore blood supply to the myocardium, or heart muscle. However, the myocardium still incurs damage, and as the adult heart does cannot efficiently regenerate new tissue, a fibrous scar is formed that does not contribute to contraction. In the longer term the remaining healthy heart undergoes remodelling while trying to maintain cardiac output, leading to an increased chance of developing of debilitating chronic heart failure. My research is focused primarily on understanding how to limit the loss of contractile tissue that occurs immediately after MI, but in particular the processes involved in infarct healing (inflammation, fibroblast activation & angiogenesis) and how these might be targeted therapeutically to prevent infarct expansion during repair. We also work on development of new imagingtechniques to identify vulnerable peri-infarct myocardium and on the mechanisms that support neonatal heart regeneration after injury. Research in Nutshell video For a list of up-to-date publications, please visit: Gillian Gray's Profile Page Research Group Members Name Email Viktoria Balogh s1243323@sms.ed.ac.uk Benjamin Thomas Ben.Thomas@ed.ac.uk This article was published on 2024-03-19
